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Petersburg Institute of Bioregulation and Gerontology of the North-Western Branch of the Russian Academy of Medical Sciences and the Institute of Gerontology of the Ukrainian Academy of Medical Sciences (Kiev) clinically assessed the geroprotective effects of thymic (Thymalin) and pineal Epithalamin (Epitalon) peptide bioregulators in 266 elderly and older persons during 6-8 years both peptides were given at 10 mg daily for ten consecutive days once every 6 months

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So in short, these knots are your veins' and body's natural response to the sclerotherapy process - not a complication in itself