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30 Interestingly, global Ctr1 global knockout (Ctr1 –/– ) mice die in utero a mid-way through gestation, and embryonic fibroblasts prepared from Ctr1 –/– embryos have drastically reduced levels of Cu and Cu-dependent enzyme activity, suggesting that Ctr1 plays an essential role in embryonic development in mammals

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Autres formes : aquocobalamine, nitritocobalamine