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At the same time, it also possesses a highly flexible high-affinity iron transport system that can switch different uptake strategies by sensing changes in host microenvironment iron concentrations, adapting to both commensal and pathogenic states (Mamouei et al., 2017)

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Because muscle tissue contains larger blood vessels and nerves, IM injection carries a higher risk of accidental intravascular injection, nerve irritation, and deeper bleeding, and it requires more careful anatomical knowledge