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Introduction Alzheimer’s disease (AD) is a progressive, multifactorial neurodegenerative disorder characterized pathologically by the presence of two hallmark proteins, amyloid beta (Aβ) and hyperphosphorylated tau

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In addition, patients with tophi are often at risk for uric acid-related kidney stones, since they may be over-producers of uric acid and have elevated 24-hour urinary uric acid