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They specifically hydrolyze GSH into a Cys-Gly dipeptide and 5-oxoproline, which are further broken down into Glu, Cys and Gly by (i) the Leu aminopeptidase 1 (EC 3.4.13.18) encoded by AtLAP1 and (ii) by the 5-oxoprolinase (5-OPase, EC 3.5.2.9) [11,110]
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Size (mL):3mL
However, under pathological conditions such as stroke, epilepsy, or traumatic brain injury, the excessive influx of zinc into neurons causes neurotoxicity, damage to neurons, and a reduction in GSH [11]