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As a result of impaired or reduced PK activity, ATP levels—which are crucial for maintaining the integrity and deformability of the cell—dramatically decline in PKD patients [74]

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Regarding specificity of these aptamers to FhbA, the corresponding BLI measurements were consistent with the Dot Blot data and showed some interactions with FhbA for aptamers 3, 4, 6, 7, 9, 10, 11 and 12 (Supplementary Fig