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As a result, GHK-Cu benefits research in wound settings often shows mixed patterns across studies
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Resident and mesenchymal‐derived fibroblasts respond to signalling factors from platelets, endothelial cells and macrophages, including transforming growth factor beta (TGF‐β) and PDGF, directing fibroblasts to become either pro‐fibrotic, laying down ECM proteins, or differentiating into myofibroblasts which drive wound contraction [12]
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