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In the MES-1 DEGs Gstm1, Idh1, and Lima1 were exclusively upregulated, and Gclm—downregulated

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Additional elements of the expression cassette included an FMDV IRES upstream of P1, the FMDV 3′UTR downstream of 3CD followed by a 20 nucleotide long polyA tail, as well as the T7 promoter and terminator elements 15