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The hydroxyproline content was also increased in CCl4-treated mice (Figure 7F), which was well in line with the upregulated levels of α-SMA (Figure 7G) and TGF-β (Figure 7H), whereas IL10 levels were decreased (Figure 7I) in the liver tissue

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Besides, betalains in beetroot have also been shown to inhibit oxidative metabolism of neutrophils in humans (Zielińska‐Przyjemska et al., 2009), enhance the activity of the antioxidant enzymes, superoxide dismutase, and peroxidase in irradiated mice liver, spleen, and kidney (Wroblewska et al., 2011)