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Treatment of Aβ42-injected rats with an inhibitor of dipeptidylpeptidase-4, sitagliptin, together with quercetin, a flavonol from the flavonoid group of polyphenols, significantly diminished the level of Aβ42 compared with either treatment alone but increased antioxidant protein levels (i.e., SOD, CAT) and the level of GSH and a diminution of histopathologically determined neuronal damage
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Statistical analyses Quantitation of disrupted areas, epidermal thickness, and neutrophil abundance was analyzed by the one-way ANOVA test