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The maximum recommended daily dose is 120 mg, and occasionally this quantity can be enough to induce euphoria and hallucinations

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Polarized M1 and M2 macrophages are also involved in the pathogenesis of COPD: the phagocytic capacity of M1 macrophages and the antigen-presenting properties of Th1 produce a variety of Th1 cytokines (128), e.g.IL-1β, IL-6, IL-12, and TNF-α