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The activation of VIP receptors stimulates the adenylyl cyclase to generate cytosolic cAMP that activate the cystic fibrosis transmembrane conductance regulator (CFTR), resulting in secretion of Cl − into the lumen
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They can be injected to fill cartilage defects in situ , form three-dimensional networks that match tissue architecture, and support chondrocyte adhesion, growth, and differentiation, thereby creating an optimal niche for regeneration
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