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The second category, tissue-repair peptides such as BPC-157 and TB-500, is studied instead for soft-tissue, tendon, and wound-healing effects linked to angiogenesis and cell migration rather than direct hormone stimulation
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Orphan GPCRs play important roles in physiological functions and are associated with various human diseases, such as schizophrenia, type 2 diabetes, attention deficit and hyperactivity disorder (ADHD), cognitive impairments, brain malformations, and Alzheimer’s disease