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The overall genome completeness of SAGs with 5% contamination, which would be caused either by contaminating extracellular DNA or by multiple cells being encapsulated in a single AGM, were binned into each bacterial species using metaWRAP 31 , although discrimination between contaminating DNA and DNA from captured multiple cells was difficult

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Moreover, our results highlight the essential role of vitamin B12 in homocysteine metabolism, as supplementation was associated with a significant reduction in serum homocysteine levels—an important biomarker associated with cardiovascular and neurodegenerative diseases