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Fourth, increasing lipid peroxidation can lead to the hyperoxidation of mitochondrial peroxiredoxin 3 (PRDX3), which then translocates to the plasma membrane and inhibits the function of the system x c − cystine–glutamate antiporter, which will tend to increase ferroptosis sensitivity 187
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doi: 10.1111/1523-1747.ep12294284 75 D'AmicoFTrovatoCSkarmoutsouERossiGAGranataMLongoVet al
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