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This disorder is characterized by thrombocytopenia and an abnormal giant α-granule in platelets due to impaired megakaryocyte maturation [83].FLI1 3.3.1.2 Deficiency of dense granules Every platelet has three to eight dense granules containing adenosine diphosphate (ADP), adenosine triphosphate (ATP), Ca 2+ , serotonin, and polyphosphates
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