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For instance, mutations at K296 7.43 have been associated with RP, and G90 2.57 D and A292 7.39 E mutations (superscripts refer to the general numbering system for GPCRs 9 ) cause CSNB 10

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The decreased level of GSH can further exacerbate the positive thromboinflammitary feedback loop in immunothrobosis by potentiating platelet aggregation and activation, and elevating levels of D-dimer [36-38]