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Copper chelation and interleukin-6 proinflammatory cytokine effects on expression of different proteins involved in iron metabolism in HepG2 cell line

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When cells are exposed to ferroptosis-inducing conditions, lipid peroxides seem to initially accumulate within the endoplasmic reticulum (ER) and other organelles and subsequently at the plasma membrane prior to membrane rupture 27–30 (Box 2)

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