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Targeting circadian rhythm in kidney disease: challenges and prospects - ScienceDirect

Considering the physiological role of selenoproteins in antioxidation and the detrimental effects of oxidative stress in chondrocytes, aberrant selenium metabolism is likely to disrupt cartilage homeostasis and cause arthropathic diseases via dysregulation of redox homeostasis (Fig

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Further investigation is needed to determine whether inhibiting LCAC accumulation can prevent or delay cellular senescence