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It is also the first medication approved for the treatment of idiopathic hypersomnia in adults.107,108 The efficacy and safety of sodium oxybate in the treatment of narcolepsy have been widely evaluated.109 The European guidelines for narcolepsy strongly recommend sodium oxybate for the treatment of cataplexy and EDS in both children and adults with narcolepsy.110 Sodium oxybate is a central nervous system depressant and an endogenous compound associated with the neurotransmitter GABA
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doi: 10.4021/jem.v3i1-2.157 85 Metabolic Pharmaceuticals Limited
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