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Cells contain a large number of antioxidants to prevent or repair the damage caused by ROS, as well as to regulate redox-sensitive signaling pathways

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Patients with hypothyroidism have increased intestinal permeability and “leaky gut” phenomenon, which makes the metabolic products of bacteria such as LPS and bacterial fragments easily translocate into the circulatory system, thus activating innate immunity (Tomov et al., 2005)