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It is a major source for methyl groups via its metabolite trimethylglycine (betaine) that participates in the S-adenosylmethionine synthesis pathways
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Vitamin B12–related acne tends to occur only in dosages in excess of 5,000 to 10,000 micrograms a week, which is well in excess of the 50 daily micrograms or single 2,000 mcg weekly dose I recommend
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