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Step 3, Phase II proof-of-concept: Randomized placebo-controlled trial in 80 to 200 subjects with metabolic disease, measuring fat mass by DEXA, insulin sensitivity by gold-standard clamp or IVGTT, and safety over 12 to 24 weeks
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Use in Insomnia Mouse Model: The three proteins that were successfully expressed and confirmed by their molecular weight and fluorescence (DSIP-CBBBP, CBBBP, and DSIP) were used in the insomnia mouse model
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