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It’s recommended to seek medical advice if experiencing the following or if these issues persist or worsen: swelling sensation in the body redness and pain at the injection site temporary itching of the skin mild diarrhea There may also be a risk of: congestive heart failure anaphylaxis polycythemia vera, which is a type of blood cancer peripheral vascular thrombosis, which involves blood clots pulmonary edema If experiencing difficulty breathing, swelling, and hives, patients must seek emergency medical help