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The MariTide Phase 2 data presented in November 2024 were highly significant: MariTide demonstrated robust weight loss at 52 weeks with no plateau — meaning continued weight loss trajectory at the end of the study period, unlike semaglutide and tirzepatide which show plateau effects — and significant improvements in cardiometabolic parameters

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Recent reviews describe telomere length and cancer risk as a “Goldilocks” problem: neither extreme is necessarily ideal