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Thus, inhibition of AKR1B1 reduced NF-κB-dependent inflammatory markers, and the synthesis of TNF-α stimulated by hyperglycemic conditions, and of inflammatory mediators like NO and PGE 2 (Ramana and Srivastava, 2010)

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It is an antioxidant that helps protect cells in the body and reduces inflammation or the development of various diseases such as heart disease and cancer, etc