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[DOI] [PubMed] [Google Scholar] Corbet C, Bastien E, Santiago de Jesus JP, Dierge E, Martherus R, Vander Linden C, Doix B, Degavre C, Guilbaud C, Petit L, Michiels C, Dessy C, Larondelle Y, Feron O, 2020
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All of the above findings suggest that excess ROS can induce oxidative stress in MM cells and mediate the phosphorylation of JNK and p38 in the MAPK signaling pathway, and that the ROS/JNK/p38 MAPK pathway is a potential mechanism for the apoptosis and mitochondrial dysfunction in MM cells induced by PRDX6 deficiency