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This is a joint statement from the TGA and Australia's Chief Medical Officer on concerns regarding the public health risks associated with unapproved peptide products. Australia's health leaders are increasingly concerned about
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Figure 1 Cytochrome P450-Mediated Metabolic Activation APAP metabolic activation is mainly catalyzed by the cytochrome P450 enzyme and the reactive metabolite associated with hepatotoxicity is commonly considered to be NAPQI (Streeter et al., 1984)
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