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This specific combination has been researched to prove to activate multiple regenerative pathways simultaneously: GHK-Cu facilitates the copper uptake vital for collagen and elastin cross-linking

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[DOI] [PubMed] [Google Scholar] Chang JH, Uchizono JA, and Park MS (2011) Efflux of Drugs via Transporters—The Antiabsorption Pathway, in: Oral Bioavailability: Basic Principles, Advanced Concepts, and Applications (Hu M and Li X eds), pp 111–126, Wiley, New Jersey