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QCA induced a dose-dependent ROS generation and catalase effectively reduced the level of ROS, suggesting that cinnamaldehyde released from QCA causes the generation of ROS including mainly H 2 O 2 and QM generation is inhibited by catalase

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For example, when the promoter of miR-137 is highly methylated, the cell’s ability to uptake glutamine is enhanced, thereby reducing its inhibitory effect on the glutamine transporter ASCT2 [93]