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Au(III) porphyrins target the mitochondrial heat shock protein 60, 103,104 whereas Au(III) mesoporphyrin IX target cysteine thiol containing proteins, thioredoxin, deubiquitinase, and heat shock protein 90 via an arylation of the meso carbon and sulfur atom of cysteine in a C–S bond formation (Chart 2)

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Among the various buffers tested, FLIP-G exhibited maximum stability and efficiency in TBS buffer (pH 7.2)