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Biologics used to treat psoriatic arthritis include: Tumor necrosis factor (TNF) inhibitors, such as etanercept (Enbrel), certolizumab (Cimzia), adalimumab (Humira), infliximab (Remicade) and golimumab (Simponi) Interlukin 17 inhibitors, including secukinumab (Cosentyx), brodalumab (Siliq), and ixekizumab (Taltz) Interleukin-12 and -23 (IL-12/23) inhibitors, such as ustekinumab (Stelara) JAK inhibitors, including tofacitinib (Xeljanz) Biologics may be used on their own or in combination with traditional DMARDs