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Elisa Dell’Aglio 1 and Amna Mhamdi 2 1 Institut National des Sciences Appliquées-Lyon, 69100 Villeurbanne, France 2 Ghent University, Department of Plant Biotechnology and Bioinformatics, and VIB Center for Plant Systems Biology, 9052 Ghent, Belgium Address correspondence to [email protected] Ascorbate (vitamin C) is one of the main redox buffers required for metabolizing reactive oxygen species

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HSCs are activated by such factors as ROS, lipid peroxidation products (MDA and HNE), and TGF-β released when adjacent cells including hepatocyte, Kupffer cells, and endothelial cells are injured