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Jabaudon et al., 2000), due to decreased uptake, increased vesicular release, and non-vesicular release, inhibit System Xc-, hindering cystine-glutamate exchange and thereby suppressing GSH production and GPX4 function, which triggers ferroptosis (Fan et al., 2023
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Additionally, studies have identified the immune-enhancing properties of modulating TME ROS levels, guiding the selection of nanocarrier materials for nanodrug construction (135)
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