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BSO treatment showed increased expression of Dnmt3a and 3b and decreased Tet2 and 3 transcripts, and it was not wholly restored after treatment withdrawal at different time points, as was shown by real-time PCR analyses (Fig

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Opposing effects of glutathione (GSH) depletion and follicle-stimulating hormone on reactive oxygen species and apoptosis in cultured preovulatory rat follicles