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In the past the Schilling test was the gold standard method to evaluate the functional capacity of the ileal IF‑B12 receptor and required the use of cobalt-labeled B12
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4) Blood Disorders Certain conditions affecting blood and bone marrow — including some leukaemias and myeloproliferative disorders such as polycythaemia vera — can cause elevated B12 due to increased production of B12‑binding proteins by white blood cells
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