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AOD9604 and β3-AR Knockout Research Research using β3-adrenergic receptor knockout mice established that AOD9604’s chronic in vivo lipolytic actions are mediated in part by modulating the expression of β3-AR in adipose tissue — a mechanism shared with intact hGH — with the restoration of depressed β3-AR RNA levels in obese animals to lean-comparable levels identified as a key pathway of sustained lipolytic sensitisation

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